1. Gene
  2. a - nonagouti Gene

a - nonagouti Gene

Mus musculus

Also known as As; ASP; A; ASIP

Gene ID: 50518 | Gene type: protein coding

About a

Summary

Enables type 3 Melanocortin Receptor binding activity and type 4 Melanocortin Receptor binding activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within several processes, including adult feeding behavior; melanin biosynthetic process; and melanosome transport. Predicted to be active in extracellular space. Is expressed in forelimb epithelium; hair bulb; hindlimb epithelium; and skin. Used to study obesity and type 2 diabetes mellitus. Orthologous to human ASIP (agouti signaling protein). [provided by Alliance of Genome Resources, Apr 2022]

a Products(1)

mRNA Protein Name
NM_015770.3 NP_056585.2 agouti-signaling protein precursor
Protein Preferred Names Protein Names

agouti-signaling protein

agouti coat color protein

agouti signal protein

agouti switch protein

non-agouti

Orthologs Information

Species Symbol Source ID
Canis familiaris a NCBI
Felis catus a NCBI
Macaca fascicularis a NCBI
Canis lupus familiaris a NCBI
Susscrofa domestica a NCBI
Leporidae a NCBI
Rattus norvegicus a NCBI
Macaca mulatta a NCBI