2. Gene
  3. Ctss - cathepsin S Gene

Ctss - cathepsin S Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 50654 | Gene type: protein coding

About Ctss

Primary_assembly 2: 183,086,437-183,114,483 forward strand.mRatBN7.2:CM026975.1

This gene has 3 transcripts (splice variants), 270 orthologues, 27 paralogues and is associated with 29 phenotypes. Biased expression in Spleen (RPKM 78.2), Brain (RPKM 595.9) and 9 other tissues.

Summary

Enables cysteine-type peptidase activity. Involved in bone resorption; metanephros development; and regulation of sensory perception of pain. Located in cell surface. Biomarker of intracranial aneurysm. Human ortholog(s) of this gene implicated in neuropathy. Orthologous to human CTSS (Cathepsin S). [provided by Alliance of Genome Resources, Apr 2022]

Ctss Products(1)

mRNA Protein Name
NM_017320.2 NP_059016.2 cathepsin S preproprotein

Ctss Protein Structure

Inhibitor_I29

Inhibitor_I29: smart00848 (36 - 95)

Peptidase_C1

Peptidase_C1: pfam00112 (123 - 338)

  • 0
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  • 341 a.a.
Protein Preferred Names Protein Names

cathepsin S

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70226 Cathepsin S, human / Unkown
HY-RS03344 CTSS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03345 Ctss Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03346 Ctss Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctss NCBI NCBI:1520
Mus musculus Ctss NCBI NCBI:13040