Ube2j1 - ubiquitin-conjugating enzyme E2J 1 Gene

Also Known as Ncube; Ubc6p; Ncube1; NCUBE-1; 0710008M05Rik; 1110030I22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56228

Summary

Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein Ligase binding activity. Acts upstream of or within regulation of tumor necrosis factor production; spermatid development; and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; nervous system; reproductive system; sensory organ; and skeleton. Orthologous to human UBE2J1 (ubiquitin conjugating enzyme E2 J1). [provided by Alliance of Genome Resources, Apr 2022]

Ube2j1 Products (2)

mRNA Protein Name
NM_001355494.1 NP_001342423.1 ubiquitin-conjugating enzyme E2 J1 isoform 2
NM_019586.4 NP_062532.2 ubiquitin-conjugating enzyme E2 J1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within ERAD pathway IDA
IDA: Inferred from direct assay
24020373 MGI
acts upstream of or within regulation of macrophage cytokine production IGI
IGI: Inferred from genetic interaction
24020373 MGI
acts upstream of or within regulation of tumor necrosis factor production IGI
IGI: Inferred from genetic interaction
24020373 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
25320092 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 J1

  • E2 ubiquitin-conjugating enzyme J1

  • non-canonical ubiquitin-conjugating enzyme 1

  • ubiquitin-conjugating enzyme E2, J1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15350 UBE2J1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20203 Ube2j1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26707 Ube2j1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2j1 NCBI NCBI:51465