Clip1 - CAP-GLY domain containing linker protein 1 Gene

Also Known as Rsn; CYLN1; Clip50; restin; CLIP170; CLIP-170; mKIAA4046; 1110007I12Rik; 4631429H07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56430

Summary

Enables microtubule plus-end binding activity. Acts upstream of or within protein transport into plasma membrane raft. Located in microtubule plus-end and nuclear envelope. Is expressed in several structures, including brain; early conceptus; heart; and spleen. Orthologous to human CLIP1 (CAP-Gly domain containing linker protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Clip1 Products (8)

mRNA Protein Name
NM_001291229.1 NP_001278158.1 CAP-Gly domain-containing linker protein 1 isoform b
NM_001347468.1 NP_001334397.1 CAP-Gly domain-containing linker protein 1 isoform c
NM_001359220.1 NP_001346149.1 CAP-Gly domain-containing linker protein 1 isoform d
NM_001359221.1 NP_001346150.1 CAP-Gly domain-containing linker protein 1 isoform e
NM_001359222.1 NP_001346151.1 CAP-Gly domain-containing linker protein 1 isoform f
NM_001359223.1 NP_001346152.1 CAP-Gly domain-containing linker protein 1 isoform g
NM_001359224.1 NP_001346153.1 CAP-Gly domain-containing linker protein 1 isoform h
NM_019765.5 NP_062739.2 CAP-Gly domain-containing linker protein 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
11290329 MGI
enables microtubule plus-end binding IDA
IDA: Inferred from direct assay
16148041 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11290329 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein transport into plasma membrane raft IMP
IMP: Inferred from mutant phenotype
18511518 MGI
Cellular Component GO Annotation Evidence References Source
located in microtubule IDA
IDA: Inferred from direct assay
18854161 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
11290329 MGI
located in microtubule plus-end IDA
IDA: Inferred from direct assay
16954346 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
26506308 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CAP-Gly domain-containing linker protein 1

  • Clip 170

  • Reed-Steinberg cell-espressed intermediate filament-associated protein

  • cytoplasmic linker protein 170

  • cytoplasmic linker protein 50

  • restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-171155 CLIP1-LTK fusion protein regulator-1 Inhibitor / Unkown
HY-RS02810 CLIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20887 Clip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27404 Clip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clip1 NCBI NCBI:6249