Dynll1 - dynein light chain LC8-type 1 Gene

Also Known as Pin; Dlc8; Dnclc1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56455

Summary

Enables dynein intermediate chain binding activity; protein C-terminus binding activity; and protein domain specific binding activity. Acts upstream of or within intraciliary retrograde transport; motile cilium assembly; and positive regulation of non-motile cilium assembly. Located in cytoskeleton; cytosol; and membrane. Part of cytoplasmic dynein complex. Is expressed in several structures, including central nervous system; heart; liver; lung; and sensory organ. Orthologous to human DYNLL1 (dynein light chain LC8-type 1). [provided by Alliance of Genome Resources, Apr 2022]

Dynll1 Products (1)

mRNA Protein Name
NM_019682.5 NP_062656.3 dynein light chain 1, cytoplasmic

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables dynein intermediate chain binding IPI
IPI: Inferred from physical interaction
11148215 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11163258 MGI
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
16098226 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within intraciliary retrograde transport IMP
IMP: Inferred from mutant phenotype
25294941 MGI
acts upstream of or within mitocytosis IMP
IMP: Inferred from mutant phenotype
34048705 MGI
acts upstream of or within motile cilium assembly IMP
IMP: Inferred from mutant phenotype
25294941 MGI
acts upstream of or within positive regulation of non-motile cilium assembly IGI
IGI: Inferred from genetic interaction
25294941 MGI
acts upstream of or within positive regulation of non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
25294941 MGI
acts upstream of or within regulation of mitochondrial membrane potential IMP
IMP: Inferred from mutant phenotype
34048705 MGI
Cellular Component GO Annotation Evidence References Source
part of cytoplasmic dynein complex IPI
IPI: Inferred from physical interaction
25294941 MGI
located in cytoskeleton IDA
IDA: Inferred from direct assay
15136728 MGI
located in cytosol IDA
IDA: Inferred from direct assay
15136728 MGI
part of dynein complex IDA
IDA: Inferred from direct assay
14561217 MGI
located in membrane IDA
IDA: Inferred from direct assay
15136728 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein light chain 1, cytoplasmic

  • 8 kDa dynein light chain

  • 8kD LC

  • 8kDa LC

  • dynein, cytoplasmic, light chain 1

  • dynein, cytoplasmic, light peptide

  • mPIN

  • protein inhibitor of neuronal nitric oxide synthase

  • protein inhibitor of nitric oxide synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04088 DYNLL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19253 Dynll1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25742 Dynll1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dynll1 NCBI NCBI:8655