Elf4 - E74-like factor 4 (ets domain transcription factor) Gene

Also Known as Mef; Gm9907

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56501

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in NK T cell proliferation; natural killer cell proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in PML body. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human ELF4 (E74 like ETS transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Elf4 Products (2)

mRNA Protein Name
NM_001381876.1 NP_001368805.1 ETS-related transcription factor Elf-4
NM_019680.2 NP_062654.2 ETS-related transcription factor Elf-4

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in NK T cell proliferation IDA
IDA: Inferred from direct assay
12387738 MGI
involved in natural killer cell proliferation IDA
IDA: Inferred from direct assay
12387738 MGI
involved in negative regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
34326534 MGI
involved in negative regulation of interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
34326534 MGI
involved in negative regulation of interleukin-6 production IMP
IMP: Inferred from mutant phenotype
34326534 MGI
involved in negative regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
35266071 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12387738 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12387738 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS-related transcription factor Elf-4

  • E74-like factor 4

  • myeloid elf-1-like factor

  • myeloid elf-1 like factor

  • myeloid elf-1-like factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150612 (R)-STU104 Inhibitor 99.91% Unkown
HY-150612S (R)-STU104-d6 99.90% Unkown
HY-RS04301 ELF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21334 Elf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27853 Elf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elf4 NCBI NCBI:2000