Brinp1 - bone morphogenic protein/retinoic acid inducible neural specific 1 Gene

Also Known as Dbc1; BRINP; Fam5a; Dbccr1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56710

Summary

Involved in cellular response to retinoic acid; negative regulation of mitotic cell cycle; and positive regulation of neuron differentiation. Acts upstream of or within several processes, including behavioral fear response; maternal behavior; and short-term memory. Predicted to be located in cytoplasm. Predicted to be active in dendrite; endoplasmic reticulum; and neuronal cell body. Is expressed in central nervous system; dorsal root ganglion; and submandibular gland primordium. Used to study attention deficit hyperactivity disorder and autism spectrum disorder. Orthologous to human BRINP1 (BMP/retinoic acid inducible neural specific 1). [provided by Alliance of Genome Resources, Apr 2022]

Brinp1 Products (1)

mRNA Protein Name
NM_019967.2 NP_064351.2 BMP/retinoic acid-inducible neural-specific protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25732823 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within behavioral fear response IMP
IMP: Inferred from mutant phenotype
24528488 MGI
involved in brain development IMP
IMP: Inferred from mutant phenotype
27042284 MGI
acts upstream of or within cell population proliferation IMP
IMP: Inferred from mutant phenotype
25732823 MGI
involved in cellular response to retinoic acid IDA
IDA: Inferred from direct assay
20025061 MGI
involved in central nervous system neuron development IDA
IDA: Inferred from direct assay
20025061 MGI
acts upstream of or within exploration behavior IMP
IMP: Inferred from mutant phenotype
27042284 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
25732823 MGI
acts upstream of or within homeostasis of number of cells within a tissue IMP
IMP: Inferred from mutant phenotype
29960053 MGI
acts upstream of or within maternal behavior IMP
IMP: Inferred from mutant phenotype
27042284 MGI
involved in negative regulation of mitotic cell cycle IDA
IDA: Inferred from direct assay
20025061 MGI
acts upstream of or within negative regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
24528488 MGI
acts upstream of neurogenesis IMP
IMP: Inferred from mutant phenotype
24528488 MGI
acts upstream of or within proteasomal protein catabolic process IMP
IMP: Inferred from mutant phenotype
25732823 MGI
acts upstream of or within protein stabilization IMP
IMP: Inferred from mutant phenotype
25732823 MGI
acts upstream of or within short-term memory IMP
IMP: Inferred from mutant phenotype
27042284 MGI
acts upstream of or within social behavior IMP
IMP: Inferred from mutant phenotype
24528488 MGI
acts upstream of or within vocalization behavior IMP
IMP: Inferred from mutant phenotype
27042284 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BMP/retinoic acid-inducible neural-specific protein 1

  • BMP/retinoic acid-inducible neural-specific protein (BRINP)

  • deleted in bladder cancer chromosome region candidate 1

  • deleted in bladder cancer protein 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01620 BRINP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21828 Brinp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brinp1 NCBI NCBI:1620