Ube2l6 - ubiquitin-conjugating enzyme E2L 6 Gene

Also Known as RIG-B; UBCH8; Ubce8; Ubcm8; 2810489I21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56791

Summary

Enables ISG15 transferase activity. Acts upstream of or within ISG15-protein conjugation and modification-dependent protein catabolic process. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in nucleus. Is expressed in liver. Orthologous to human UBE2L6 (Ubiquitin Conjugating Enzyme E2 L6). [provided by Alliance of Genome Resources, Apr 2022]

Ube2l6 Products (1)

mRNA Protein Name
NM_019949.2 NP_064333.2 ubiquitin/ISG15-conjugating enzyme E2 L6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ISG15 transferase activity IDA
IDA: Inferred from direct assay
16139798 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15485925 MGI
enables ubiquitin-like protein transferase activity IDA
IDA: Inferred from direct assay
15485925 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ISG15-protein conjugation IDA
IDA: Inferred from direct assay
16139798 MGI
acts upstream of or within modification-dependent protein catabolic process IDA
IDA: Inferred from direct assay
15485925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin/ISG15-conjugating enzyme E2 L6

  • E2 ubiquitin conjugating enzyme

  • E2 ubiquitin-conjugating enzyme L6

  • ubiquitin carrier protein L6

  • ubiquitin-conjugating enzyme 8

  • ubiquitin-protein ligase L6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15354 UBE2L6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21971 Ube2l6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28488 Ube2l6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2l6 NCBI NCBI:9246