1. Gene
  2. Uts2r - urotensin 2 receptor Gene

Uts2r - urotensin 2 receptor Gene

Rattus norvegicus

Also known as Senr; Gpr14; UR-2-R

Gene ID: 57305 | Gene type: protein coding

About Uts2r

Primary_assembly 10: 106,438,092-106,439,252 forward strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 54 orthologues, 24 paralogues and is associated with 9 phenotypes.

Summary

Enables urotensin II receptor activity. Involved in several processes, including positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of circadian sleep/wake cycle, wakefulness; and regulation of blood pressure. Located in early endosome; plasma membrane; and recycling endosome. Used to study acute kidney failure; endomyocardial fibrosis; and hypertension. Biomarker of cardiomyopathy and myocardial infarction. Orthologous to human UTS2R (urotensin 2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Uts2r Products(1)

mRNA Protein Name
NM_020537.1 NP_065412.1 urotensin-2 receptor

Uts2r Protein Structure

7tmA_UII-R

7tmA_UII-R: cd14999 (53 - 78)

7tmA_UII-R

7tmA_UII-R: cd14999 (53 - 327)

7tmA_UII-R

7tmA_UII-R: cd14999 (85 - 109)

7tmA_UII-R

7tmA_UII-R: cd14999 (122 - 152)

7tmA_UII-R

7tmA_UII-R: cd14999 (164 - 185)

7tmA_UII-R

7tmA_UII-R: cd14999 (207 - 236)

7tmA_UII-R

7tmA_UII-R: cd14999 (251 - 281)

7tmA_UII-R

7tmA_UII-R: cd14999 (295 - 320)

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  • 386 a.a.
Protein Preferred Names Protein Names

urotensin-2 receptor

G-protein coupled receptor 14

G-protein coupled sensory epithelial neuropeptide-like receptor

UR-II-R

putative G protein-coupled receptor (SENR)

urotensin II receptor

Orthologs Information

Species Symbol Source ID
Homo sapiens Uts2r NCBI NCBI:2837