Srsf4 - serine and arginine-rich splicing factor 4 Gene

Also Known as SRp75; Sfrs4; MNCb-2616; 5730499P16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57317

Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Sep 2010]

Srsf4 Products (6)

mRNA Protein Name
NM_001369308.1 NP_001356237.1 serine/arginine-rich splicing factor 4 isoform a
NM_001369309.1 NP_001356238.1 serine/arginine-rich splicing factor 4 isoform a
NM_001369310.1 NP_001356239.1 serine/arginine-rich splicing factor 4 isoform a
NM_001369311.1 NP_001356240.1 serine/arginine-rich splicing factor 4 isoform a
NM_001369312.1 NP_001356241.1 serine/arginine-rich splicing factor 4 isoform c
NM_020587.2 NP_065612.2 serine/arginine-rich splicing factor 4 isoform b

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
24029230 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 4

  • splicing factor, arginine/serine-rich 4 (SRp75)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13795 SRSF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22831 Srsf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29346 Srsf4 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srsf4 NCBI NCBI:6429