P2ry4 - pyrimidinergic receptor P2Y, G-protein coupled, 4 Gene

Also Known as P2Y4; P2Y4R

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57385

About P2ry4

Chromosome X: 99,633,760-99,638,475 reverse strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 168 orthologues, 13 paralogues and is associated with 2 phenotypes. Biased expression in liver adult (RPKM 7.1), large intestine adult (RPKM 3.5) and 5 other tissues.

Summary

Enables G protein-coupled UTP receptor activity. Acts upstream of or within cellular response to prostaglandin E stimulus and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Is expressed in skeletal muscle. Orthologous to human P2RY4 (pyrimidinergic receptor P2Y4). [provided by Alliance of Genome Resources, Apr 2022]

P2ry4 Products (1)

mRNA Protein Name
NM_020621.4 NP_065646.1 P2Y purinoceptor 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled UTP receptor activity IDA
IDA: Inferred from direct assay
11259526 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to prostaglandin E stimulus IDA
IDA: Inferred from direct assay
23479225 MGI
acts upstream of or within transepithelial chloride transport IDA
IDA: Inferred from direct assay
11259526 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2ry4 Protein Structure

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 312)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 58)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (65 - 90)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (103 - 133)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (145 - 167)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (192 - 221)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (233 - 263)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (280 - 305)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 4

  • P2Y4 receptor

  • purinergic receptor P2Y, G-protein coupled, 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09931 P2RY4 Human Pre-designed siRNA Set A / Unkown
HY-RS09932 P2ry4 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09933 P2ry4 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2ry4 NCBI NCBI:5030