PTPRCAP - protein tyrosine phosphatase receptor type C associated protein Gene

Homo sapiens

Also known as LPAP; CD45-AP

Gene ID: 5790 | Gene type: protein coding

About PTPRCAP

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:67,435,510-67,437,682 (from NCBI)

This gene has 1 transcript (splice variant) and 88 orthologues. Biased expression in spleen (RPKM 58.4), lymph node (RPKM 46.1) and 9 other tissues.

Summary

The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine Phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein. [provided by RefSeq, Jul 2008]

PTPRCAP Products(1)

mRNA	Protein	Name
NM_005608.3	NP_005599.1	protein tyrosine phosphatase receptor type C-associated protein precursor

Protein Preferred Names

Protein Names

protein tyrosine phosphatase receptor type C-associated protein

CD45 associated protein

Related Diseases

Diseases

Alias

Gallbladder Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Gallbladder

Epidermoid Gallbladder Carcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11435	PTPRCAP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PTPRCAP	VGNC	VGNC:76613
Bos taurus	PTPRCAP	VGNC	VGNC:33547
Mus musculus	PTPRCAP	MGD	MGI:97811
Felis catus	PTPRCAP	VGNC	VGNC:104318
Rattus norvegicus	PTPRCAP	RGD	RGD:1559601

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