Rsad2 - radical S-adenosyl methionine domain containing 2 Gene

Also Known as Vig1; cig5; 2510004L01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58185

Summary

Predicted to enable 4 iron, 4 sulfur cluster binding activity and protein self-association. Involved in several processes, including negative regulation of viral genome replication; positive regulation of T-helper 2 cell cytokine production; and positive regulation of Toll-like Receptor signaling pathway. Located in endoplasmic reticulum and lipid droplet. Human ortholog(s) of this gene implicated in respiratory syncytial virus infectious disease. Orthologous to human RSAD2 (radical S-adenosyl methionine domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Rsad2 Products (1)

mRNA Protein Name
NM_021384.4 NP_067359.2 radical S-adenosyl methionine domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21435586 MGI
Biological Process GO Annotation Evidence References Source
involved in CD4-positive, alpha-beta T cell activation IMP
IMP: Inferred from mutant phenotype
19047684 MGI
involved in CD4-positive, alpha-beta T cell differentiation IMP
IMP: Inferred from mutant phenotype
19047684 MGI
involved in defense response to virus IDA
IDA: Inferred from direct assay
17686841 MGI
involved in negative regulation of viral genome replication IMP
IMP: Inferred from mutant phenotype
21880757 MGI
involved in positive regulation of T-helper 2 cell cytokine production IMP
IMP: Inferred from mutant phenotype
19047684 MGI
involved in positive regulation of toll-like receptor 7 signaling pathway IMP
IMP: Inferred from mutant phenotype
21435586 MGI
involved in positive regulation of toll-like receptor 9 signaling pathway IMP
IMP: Inferred from mutant phenotype
21435586 MGI
involved in response to virus IMP
IMP: Inferred from mutant phenotype
21880757 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
23160199 MGI
located in lipid droplet IDA
IDA: Inferred from direct assay
19920176 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

radical S-adenosyl methionine domain-containing protein 2

  • VHSV-induced-like protein

  • viperin

  • viral hemorrhagic septicemia virus (VHSV)-induced gene 1

  • virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12297 RSAD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20486 Rsad2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26994 Rsad2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rsad2 NCBI NCBI:91543