1. Gene
  2. Ptafr - platelet-activating factor receptor Gene

Ptafr - platelet-activating factor receptor Gene

Rattus norvegicus
Gene ID: 58949 | Gene type: protein coding

About Ptafr

Primary_assembly 5: 144,765,976-144,795,251 forward strand.mRatBN7.2:CM026978.1

This gene has 3 transcripts (splice variants), 223 orthologues, 6 paralogues and is associated with 21 phenotypes. Biased expression in Spleen (RPKM 63.9), Lung (RPKM 25.3) and 9 other tissues.

Summary

Enables mitogen-activated protein kinase binding activity and platelet activating factor receptor activity. Involved in several processes, including positive regulation of gene expression; positive regulation of transport; and regulation of cellular extravasation. Located in plasma membrane. Used to study several diseases, including acute kidney failure; neutropenia; perinatal necrotizing enterocolitis; pleurisy; and transient cerebral ischemia. Biomarker of conjunctivitis; sciatic neuropathy; and transient cerebral ischemia. Orthologous to human PTAFR (platelet activating factor receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptafr Products(1)

mRNA Protein Name
NM_053321.2 NP_445773.1 platelet-activating factor receptor
Protein Preferred Names Protein Names

platelet-activating factor receptor

PAF-R

PAFr

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptafr NCBI NCBI:5724