Thap11 - THAP domain containing 11 Gene

Also Known as Ronin; CTG-B43a; CTG-B45d; 2810036E22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 59016

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Is expressed in 1-cell stage embryo; brain ventricular layer; forelimb bud; inferior colliculus; and oocyte. Orthologous to human THAP11 (THAP domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Thap11 Products (1)

mRNA Protein Name
NM_021513.2 NP_067488.1 THAP domain-containing protein 11

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
26876175 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
26876175 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell population proliferation IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within electron transport chain IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within positive regulation of androgen receptor activity IMP
IMP: Inferred from mutant phenotype
26876175 MGI
acts upstream of or within regulation of mitochondrial transcription IMP
IMP: Inferred from mutant phenotype
26876175 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

THAP domain-containing protein 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14471 THAP11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20604 Thap11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27112 Thap11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Thap11 NCBI NCBI:57215