Clstn2 - calsyntenin 2 Gene

Also Known as Cs2; CSTN2; Cst-2; mKIAA4134; 2900042C18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64085

Summary

Predicted to enable calcium ion binding activity. Acts upstream of or within positive regulation of synapse assembly and positive regulation of synaptic transmission. Located in cell surface; postsynaptic density; and postsynaptic membrane. Is integral component of postsynaptic density membrane. Is active in glutamatergic synapse. Is expressed in several structures, including brain; ear; forelimb bud; heart; and paraxial mesenchyme. Orthologous to human CLSTN2 (calsyntenin 2). [provided by Alliance of Genome Resources, Apr 2022]

Clstn2 Products (2)

mRNA Protein Name
NM_001413406.1 NP_001400335.1 calsyntenin-2 isoform 2 precursor
NM_022319.3 NP_071714.2 calsyntenin-2 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in associative learning IMP
IMP: Inferred from mutant phenotype
26171716 MGI
involved in inhibitory synapse assembly IMP
IMP: Inferred from mutant phenotype
26171716 MGI
acts upstream of or within positive regulation of synapse assembly IGI
IGI: Inferred from genetic interaction
24613359 MGI
acts upstream of or within positive regulation of synaptic transmission IGI
IGI: Inferred from genetic interaction
24613359 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
24613359 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12498782 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
24613359 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
12498782 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
12498782 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calsyntenin-2

  • alc-gamma

  • alcadein-gamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02841 CLSTN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21107 Clstn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27626 Clstn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clstn2 NCBI NCBI:64084