Pi4ka - phosphatidylinositol 4-kinase alpha Gene

Rattus norvegicus

Also known as Pik4ca

Gene ID: 64161 | Gene type: protein coding

About Pi4ka

Primary_assembly 11: 83,609,069-83,724,080 forward strand.mRatBN7.2:CM026984.1

This gene has 1 transcript (splice variant), 210 orthologues, 9 paralogues and is associated with 18 phenotypes. Biased expression in Brain (RPKM 24.2), Kidney (RPKM 119.1) and 9 other tissues.

Summary

Enables 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in several processes, including phosphatidylinositol phosphate biosynthetic process; phosphatidylinositol-mediated signaling; and viral replication complex formation and maintenance. Predicted to act upstream of or within phosphorylation. Located in Golgi-associated vesicle membrane. Orthologous to human PI4KA (phosphatidylinositol 4-kinase alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pi4ka Products(1)

mRNA	Protein	Name
NM_022301.2	NP_071637.2	phosphatidylinositol 4-kinase alpha

Pi4ka Protein Structure

PI4K_N

PI4Ka

PI4Kc_III_alpha

0
400
800
1200
1600
2000
2114 a.a.

Protein Preferred Names

Protein Names

phosphatidylinositol 4-kinase alpha

PI4-kinase alpha	PI4K-alpha
leuserpin 2	phosphatidylinositol 4-kinase a
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	ptdIns-4-kinase alpha

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125118	GSK-A1	Inhibitor	≥99.0%	Unkown
HY-100603	GSK-F1		95.00%	Unkown
HY-RS10466	PI4KA Human Pre-designed siRNA Set A		/	Unkown
HY-RS10467	Pi4ka Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS10468	Pi4ka Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pi4ka	NCBI	NCBI:5297

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