2. Gene
  3. Slc5a2 - solute carrier family 5 member 2 Gene

Slc5a2 - solute carrier family 5 member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sglt2

Gene ID: 64522 | Gene type: protein coding

About Slc5a2

Primary_assembly 1: 182,847,106-182,853,306 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 200 orthologues, 13 paralogues and is associated with 4 phenotypes. Biased expression in Kidney (RPKM 171.3) and Lung (RPKM 4.8).

Summary

Enables glucose:sodium symporter activity. Involved in glucose transmembrane transport; negative regulation of urine volume; and renal potassium excretion. Located in brush border membrane. Is integral component of membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in renal glycosuria. Orthologous to human SLC5A2 (solute carrier family 5 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc5a2 Products(1)

mRNA Protein Name
NM_022590.2 NP_072112.2 sodium/glucose cotransporter 2

Slc5a2 Protein Structure

SLC5-6-like_sbd

SLC5-6-like_sbd: cl00456 (21 - 669)

  • 0
  • 200
  • 400
  • 600
  • 670 a.a.
Protein Preferred Names Protein Names

sodium/glucose cotransporter 2

Na(+)/glucose cotransporter 2

low affinity Na-dependent glucose transporter (SGLT2)

low affinity sodium-glucose cotransporter

solute carrier family 5 (sodium/glucose cotransporter), member 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13286 SLC5A2 Human Pre-designed siRNA Set A / Unkown
HY-RS13288 Slc5a2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc5a2 NCBI NCBI:6524