Ntsr2 - neurotensin receptor 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64636

About Ntsr2

Primary_assembly 6: 39,424,324-39,431,014 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 79 orthologues, 14 paralogues and is associated with 1 phenotype. Restricted expression toward (RPKM 7.4).

Summary

Enables identical protein binding activity. Involved in positive regulation of ERK1 and ERK2 cascade. Located in several cellular components, including dendritic shaft; perikaryon; and trans-Golgi network. Orthologous to human NTSR2 (Neurotensin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr2 Products (1)

mRNA Protein Name
NM_022695.2 NP_073186.1 neurotensin receptor type 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
17188644 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17188644 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
16564027 RGD
involved in positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
12084713 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
16564027 RGD
located in dendritic shaft IDA
IDA: Inferred from direct assay
16564027 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
16564027 RGD
located in trans-Golgi network IDA
IDA: Inferred from direct assay
16564027 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ntsr2 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 368)

7tm_GPCRs

7tm_GPCRs: cd14964 (34 - 58)

7tm_GPCRs

7tm_GPCRs: cd14964 (68 - 90)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 130)

7tm_GPCRs

7tm_GPCRs: cd14964 (153 - 169)

7tm_GPCRs

7tm_GPCRs: cd14964 (203 - 226)

7tm_GPCRs

7tm_GPCRs: cd14964 (295 - 317)

7tm_GPCRs

7tm_GPCRs: cd14964 (336 - 361)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
Protein Preferred Names Protein Names

neurotensin receptor type 2

  • NT-R-2

  • NTR2 receptor

  • high-affinity levocabastine-sensitive neurotensin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11845 DOTA-NT-20.3-IPBA Modulator / Unkown
HY-RS09641 NTSR2 Human Pre-designed siRNA Set A / Unkown
HY-RS09642 Ntsr2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09643 Ntsr2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ntsr2 NCBI NCBI:23620