Aoc1 - amine oxidase, copper containing 1 Gene

Also Known as Abp; Abp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65029

Summary

Enables diamine oxidase activity and organic cyclic compound binding activity. Involved in cellular response to copper ion starvation and response to Antibiotic. Acts upstream of or within amiloride transport. Located in bicellular tight junction. Orthologous to human AOC1 (amine oxidase copper containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Aoc1 Products (1)

mRNA Protein Name
NM_022935.2 NP_075224.2 amiloride-sensitive amine oxidase [copper-containing] precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables diamine oxidase activity IDA
IDA: Inferred from direct assay
9399025 RGD
enables organic cyclic compound binding IPI
IPI: Inferred from physical interaction
8375402 RGD
enables putrescine oxidase activity IDA
IDA: Inferred from direct assay
7626074 RGD
Cellular Component GO Annotation Evidence References Source
located in bicellular tight junction IDA
IDA: Inferred from direct assay
18855986 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amiloride-sensitive amine oxidase [copper-containing]

  • DAO

  • amiloride binding protein 1 (amine oxidase, copper-containing)

  • amiloride-binding protein 1

  • amiloride-sensitive amine oxidase

  • amine oxidase copper domain-containing protein 1

  • diamine oxidase

  • histaminase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-143721 SSAO inhibitor-2 Inhibitor / Unkown
HY-143723 SSAO inhibitor-3 Inhibitor / Unkown
HY-RS00771 AOC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17364 Aoc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23818 Aoc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aoc1 NCBI NCBI:26