Slit1 - slit guidance ligand 1 Gene

Also Known as MEGF4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65047

Summary

Enables heparan sulfate proteoglycan binding activity. Involved in brain development; negative regulation of axon extension involved in axon guidance; and spinal cord development. Located in extracellular space. Orthologous to human SLIT1 (slit guidance ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Slit1 Products (1)

mRNA Protein Name
NM_022953.2 NP_075242.1 slit homolog 1 protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparan sulfate proteoglycan binding IDA
IDA: Inferred from direct assay
10364234 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15528323 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of axon extension involved in axon guidance IDA
IDA: Inferred from direct assay
15632296 RGD
involved in spinal cord development IEP
IEP: Inferred from expression pattern
10102268 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
15632296 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

slit homolog 1 protein

  • multiple EGF-like domains protein 4

  • multiple epidermal growth factor-like domains 4

  • multiple epidermal growth factor-like domains protein 4

  • slit-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13370 SLIT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13372 SLIT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20490 Slit3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21757 Slit1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28275 Slit1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slit1 NCBI NCBI:6585