2. Gene
  3. CDK15 - cyclin dependent kinase 15 Gene

CDK15 - cyclin dependent kinase 15 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PFTK2; ALS2CR7; PFTAIRE2

Gene ID: 65061 | Gene type: protein coding

About CDK15

Cytogenetic location: 2q33.1 Genomic coordinates (GRCh38): 2:201,806,429-201,895,550 (from NCBI)

This gene has 10 transcripts (splice variants), 198 orthologues and 26 paralogues. Biased expression in ovary (RPKM 1.2), gall bladder (RPKM 0.5) and 13 other tissues.

Summary

Enables protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CDK15 Products(4)

mRNA Protein Name
NM_001261435.1 NP_001248364.1 cyclin-dependent kinase 15 isoform 1
NM_001261436.1 NP_001248365.1 cyclin-dependent kinase 15 isoform 2
NM_001366386.2 NP_001353315.1 cyclin-dependent kinase 15 isoform 4
NM_139158.2 NP_631897.1 cyclin-dependent kinase 15 isoform 3

CDK15 Protein Structure

Pkinase

Pkinase: Protein kinase domain (105 - 387)

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  • 429 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 15

PFTAIRE protein kinase 2

Related Diseases

Diseases Alias
Amyotrophic Lateral Sclerosis 2, Juvenile

ALS2

Als, Juvenile

Alsj

Amyotrophic Lateral Sclerosis Type 2

Amyotrophic Lateral Sclerosis 2

Amyotrophic Lateral Sclerosis Type 2, Juvenile

Amyotrophic Lateral Sclerosis Juvenile

Amyotrophic Lateral Sclerosis Juvenile 2

Sclerosis, Lateral, Amyotrophic, Type Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02365 CDK15 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CDK15 RGD RGD:1306205
Macaca mulatta CDK15 VGNC VGNC:70951
Felis catus CDK15 VGNC VGNC:60696
Bos taurus CDK15 VGNC VGNC:106681
Canis familiaris CDK15 VGNC VGNC:39047
Mus musculus CDK15 MGD MGI:3583944
Others CDK15 NCBI