Ifi30 - interferon gamma inducible protein 30 Gene

Also Known as GILT; IP30

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65972

Summary

Predicted to enable oxidoreductase activity, acting on a sulfur group of donors. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of fibroblast proliferation; and protein stabilization. Located in lysosome. Is expressed in alimentary system; liver; and orbito-sphenoid. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Ifi30 Products (1)

mRNA Protein Name
NM_023065.3 NP_075552.2 gamma-interferon-inducible lysosomal thiol reductase precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in antigen processing and presentation of exogenous peptide antigen via MHC class I IMP
IMP: Inferred from mutant phenotype
20538950 MGI
acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II IMP
IMP: Inferred from mutant phenotype
11701933 MGI
acts upstream of or within negative regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
18218638 MGI
acts upstream of or within protein stabilization IMP
IMP: Inferred from mutant phenotype
18218638 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
11701933 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-interferon-inducible lysosomal thiol reductase

  • gamma-interferon-inducible protein IP-30

  • lysosomal thio reductase IP30

  • lysosomal thiol reductase IP30

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06554 IFI30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19445 Ifi30 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25937 Ifi30 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifi30 NCBI NCBI:10437