Txndc12 - thioredoxin domain containing 12 (endoplasmic reticulum) Gene

Also Known as ERp16; ERp19; 0610040B21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66073

Summary

Predicted to enable protein-disulfide reductase activity. Predicted to be involved in negative regulation of cell death. Predicted to act upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cranium; eye; and respiratory system. Orthologous to human TXNDC12 (thioredoxin domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

Txndc12 Products (1)

mRNA Protein Name
NM_025334.3 NP_079610.1 thioredoxin domain-containing protein 12 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
18628206 MGI
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
12930873 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 12

  • ER protein 19

  • endoplasmic reticulum protein ERp19

  • endoplasmic reticulum resident protein 19

  • ortholog of endoplasmic reticulum thioredoxin superfamily member, 18 kDa TLP19

  • thioredoxin-like protein p19

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15290 TXNDC12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21267 Txndc12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27785 Txndc12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Txndc12 NCBI NCBI:51060