Rras2 - related RAS viral (r-ras) oncogene 2 Gene

Also Known as TC21; 2610016H24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66922

Summary

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Acts upstream of or within Ras protein signal transduction and positive regulation of cell migration. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in plasma membrane. Is expressed in blood vessel; cerebral cortex; metanephros; musculature; and thymus primordium. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Orthologous to human RRAS2 (Ras related 2). [provided by Alliance of Genome Resources, Apr 2022]

Rras2 Products (1)

mRNA Protein Name
NM_025846.2 NP_080122.2 ras-related protein R-Ras2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11788587 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Ras protein signal transduction IDA
IDA: Inferred from direct assay
11788587 MGI
acts upstream of Schwann cell migration IGI
IGI: Inferred from genetic interaction
14724565 MGI
acts upstream of cell migration IGI
IGI: Inferred from genetic interaction
14724565 MGI
acts upstream of or within positive regulation of Schwann cell migration IGI
IGI: Inferred from genetic interaction
14724565 MGI
Cellular Component GO Annotation Evidence References Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
11788587 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein R-Ras2

  • related RAS viral (r-ras) oncogene homolog 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128574 D927 Activator 99.46% Unkown
HY-W1126235 DS02312223 Activator 98.24% Unkown
HY-RS12281 RRAS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22789 Rras2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29303 Rras2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rras2 NCBI NCBI:22800