Ddx17 - DEAD box helicase 17 Gene

Also Known as p72; Gm926; 2610007K22Rik; A430025E01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67040

Summary

This gene encodes the mouse homolog of human DEAD box polypeptide 17. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). RNA helicases of the DEAD-box family are involved in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Ddx17 Products (4)

mRNA Protein Name
NM_001040187.1 NP_001035277.1 probable ATP-dependent RNA helicase DDX17 isoform 4
NM_152806.3 NP_690019.2 probable ATP-dependent RNA helicase DDX17 isoform 3
NM_199079.2 NP_951061.1 probable ATP-dependent RNA helicase DDX17 isoform 2
NM_199080.2 NP_951062.1 probable ATP-dependent RNA helicase DDX17 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin DNA binding IDA
IDA: Inferred from direct assay
29431742 MGI
enables lncRNA binding IDA
IDA: Inferred from direct assay
29431742 MGI
enables lncRNA binding IPI
IPI: Inferred from physical interaction
30622218 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24581491 MGI
Biological Process GO Annotation Evidence References Source
involved in alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
24910439 MGI
involved in gene expression IMP
IMP: Inferred from mutant phenotype
29431742 MGI
involved in miRNA transcription IMP
IMP: Inferred from mutant phenotype
24910439 MGI
involved in myoblast differentiation IMP
IMP: Inferred from mutant phenotype
24910439 MGI
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
23022728 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX17

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

  • DEAD box protein 17

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116940 Sm4 Inhibitor 99.01% Unkown
HY-RS03632 DDX17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18995 Ddx17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25484 Ddx17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddx17 NCBI NCBI:10521