Trak1 - trafficking protein, kinesin binding 1 Gene

Also Known as hyrt; mKIAA1042; 2310001H13Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 67095

Summary

Enables GABA Receptor binding activity. Involved in anterograde axonal transport of mitochondrion. Predicted to be located in axonal growth cone; early endosome; and perinuclear region of cytoplasm. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. Is expressed in several structures, including central nervous system; dorsal root ganglion; liver; spleen; and submandibular gland primordium. Used to study Stiff-Person syndrome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 68. Orthologous to human TRAK1 (trafficking Kinesin protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Trak1 Products (12)

mRNA	Protein	Name
NM_001357968.1	NP_001344897.1	trafficking kinesin-binding protein 1 isoform 2
NM_001357969.1	NP_001344898.1	trafficking kinesin-binding protein 1 isoform 3
NM_001357970.1	NP_001344899.1	trafficking kinesin-binding protein 1 isoform 4
NM_001357972.1	NP_001344901.1	trafficking kinesin-binding protein 1 isoform 5
NM_001357973.1	NP_001344902.1	trafficking kinesin-binding protein 1 isoform 6
NM_175114.4	NP_780323.2	trafficking kinesin-binding protein 1 isoform 1
NM_001357968.1	NP_001344897.1	trafficking kinesin-binding protein 1 isoform 2
NM_001357969.1	NP_001344898.1	trafficking kinesin-binding protein 1 isoform 3
NM_001357970.1	NP_001344899.1	trafficking kinesin-binding protein 1 isoform 4
NM_001357972.1	NP_001344901.1	trafficking kinesin-binding protein 1 isoform 5
NM_001357973.1	NP_001344902.1	trafficking kinesin-binding protein 1 isoform 6
NM_175114.4	NP_780323.2	trafficking kinesin-binding protein 1 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables GABA receptor binding	IDA IDA: Inferred from direct assay	16380713	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
trafficking kinesin-binding protein 1	protein Milton

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14979	TRAK1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22874	Trak1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Trak1	NCBI	NCBI:22906