Fbxo5 - F-box protein 5 Gene

Also Known as Emi1; Fbxo31; 2510044I10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67141

Summary

Predicted to enable anaphase-promoting complex binding activity; protein kinase binding activity; and ubiquitin Ligase inhibitor activity. Involved in regulation of mitotic cell cycle. Acts upstream of or within several processes, including female gamete generation; microtubule polymerization; and negative regulation of meiotic nuclear division. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including brain ventricular layer; early conceptus; nephrogenic zone; oocyte; and rest of cerebellum marginal layer. Orthologous to human FBXO5 (F-box protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo5 Products (1)

mRNA Protein Name
NM_025995.2 NP_080271.2 F-box only protein 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15526037 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within microtubule polymerization IDA
IDA: Inferred from direct assay
17190794 MGI
acts upstream of or within negative regulation of meiotic nuclear division IDA
IDA: Inferred from direct assay
15526037 MGI
acts upstream of or within oocyte maturation IDA
IDA: Inferred from direct assay
15526037 MGI
acts upstream of or within oocyte maturation IMP
IMP: Inferred from mutant phenotype
15526037 MGI
acts upstream of or within regulation of meiotic nuclear division IDA
IDA: Inferred from direct assay
17190794 MGI
involved in regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
16809773 MGI
acts upstream of or within spindle assembly IDA
IDA: Inferred from direct assay
17190794 MGI
acts upstream of or within spindle assembly involved in female meiosis I IDA
IDA: Inferred from direct assay
17190794 MGI
acts upstream of or within vesicle organization IDA
IDA: Inferred from direct assay
17190794 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15526037 MGI
located in meiotic spindle IDA
IDA: Inferred from direct assay
15526037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 5

  • early mitotic inhibitor 1

  • f-box only protein 31

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04811 FBXO5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21570 Fbxo5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28088 Fbxo5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxo5 NCBI NCBI:26271