Ndufb8 - NADH:ubiquinone oxidoreductase subunit B8 Gene

Also Known as CI-ASHI; 2900010I05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67264

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 32. Orthologous to human NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8). [provided by Alliance of Genome Resources, Apr 2022]

Ndufb8 Products (2)

mRNA Protein Name
NM_001347447.1 NP_001334376.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform 2 precursor
NM_026061.3 NP_080337.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
19837698 MGI
part of respiratory chain complex I IDA
IDA: Inferred from direct assay
24154540 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

  • NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8

  • NADH-ubiquinone oxidoreductase ASHI subunit

  • complex I-ASHI

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-134539 IMT1 Inhibitor 99.86% Unkown
HY-RS09153 NDUFB8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18200 Ndufb8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24676 Ndufb8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndufb8 NCBI NCBI:4714