PROTAC CRBN ligand-2
PROTAC CRBN ligand-2 (12) is a Biguanide-PROTAC derivative, with an EC50 of 0.15 mM in KP4 cells. PROTAC CRBN ligand-2 (12) demonstrates the ability to alter levels of mitochondrial proteins, notably complexes I and IV.
For research use only. We do not sell to patients.
- Formula: C33H30N8O8
- Molecular Weight:666.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
Chemical Information
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Molecular Weight 666.64
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Formula C33H30N8O8
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SMILES
N=C(NC(NCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)NC(COC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)=N)N.O=CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)