Bag4 - BCL2-associated athanogene 4 Gene

Also Known as SODD; 2410112I15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67384

Summary

Predicted to enable adenyl-nucleotide exchange factor activity; chaperone binding activity; and ubiquitin protein Ligase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; positive regulation of supramolecular fiber organization; and regulation of phosphate metabolic process. Predicted to be located in plasma membrane. Predicted to be active in cytosol; membrane; and nucleus. Is expressed in foregut; heart ventricle; nose; pituitary gland; and urethra. Orthologous to human BAG4 (BAG cochaperone 4). [provided by Alliance of Genome Resources, Apr 2022]

Bag4 Products (1)

mRNA Protein Name
NM_026121.3 NP_080397.1 BAG family molecular chaperone regulator 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11527400 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to epidermal growth factor stimulus IDA
IDA: Inferred from direct assay
21712384 MGI
involved in negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
IDA: Inferred from direct assay
21712384 MGI
involved in positive regulation of actin filament polymerization IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in positive regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in positive regulation of fibroblast migration IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in positive regulation of peptidyl-serine phosphorylation IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in positive regulation of stress fiber assembly IMP
IMP: Inferred from mutant phenotype
21712384 MGI
involved in protein localization to plasma membrane IDA
IDA: Inferred from direct assay
21712384 MGI
involved in ruffle assembly IMP
IMP: Inferred from mutant phenotype
21712384 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BAG family molecular chaperone regulator 4

  • BAG-4

  • bcl-2-associated athanogene 4

  • silencer of death domains

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01345 BAG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19877 Bag4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26376 Bag4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bag4 NCBI NCBI:9530