Jarid2 - jumonji and AT-rich interaction domain containing 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 681740

Summary

Predicted to enable several functions, including Histone Demethylase activity; ubiquitin binding activity; and ubiquitin modification-dependent histone binding activity. Involved in negative regulation of cardiac muscle cell proliferation and negative regulation of cardiac muscle hypertrophy. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of ESC/E(Z) complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Jarid2 Products (8)

mRNA Protein Name
XM_039096474.1 XP_038952402.1 protein Jumonji isoform X3
XM_017600709.2 XP_017456198.1 protein Jumonji isoform X3
XM_017600710.2 XP_017456199.1 protein Jumonji isoform X3
XM_017600708.2 XP_017456197.1 protein Jumonji isoform X3
XM_039096473.1 XP_038952401.1 protein Jumonji isoform X3
XM_039096472.1 XP_038952400.1 protein Jumonji isoform X2
XM_017600711.2 XP_017456200.1 protein Jumonji isoform X4
XM_017600707.2 XP_017456196.1 protein Jumonji isoform X1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cardiac muscle cell proliferation IDA
IDA: Inferred from direct assay
26298346 RGD
involved in negative regulation of cardiac muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
26298346 RGD
involved in negative regulation of cardiac muscle hypertrophy IGI
IGI: Inferred from genetic interaction
24657879 RGD
involved in negative regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
24657879 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Jumonji

  • jumonji, AT rich interactive domain 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07030 JARID2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19784 Jarid2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26281 Jarid2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jarid2 NCBI NCBI:3720