Rraga - Ras-related GTP binding A Gene

Also Known as RAGA; FIP-1; 1300010C19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68441

Summary

Predicted to enable several functions, including GTP binding activity; protein dimerization activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; negative regulation of autophagy; and positive regulation of TORC1 signaling. Predicted to act upstream of or within regulation of cytolysis. Predicted to be located in cytoplasm. Predicted to be part of GATOR1 complex and Gtr1-Gtr2 GTPase complex. Predicted to be active in lysosome and nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human RRAGA (Ras related GTP binding A). [provided by Alliance of Genome Resources, Apr 2022]

Rraga Products (1)

mRNA Protein Name
NM_178376.3 NP_848463.1 ras-related GTP-binding protein A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTP binding IMP
IMP: Inferred from mutant phenotype
23263183 MGI
enables GTPase activity IMP
IMP: Inferred from mutant phenotype
23263183 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
29644770 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to starvation IMP
IMP: Inferred from mutant phenotype
23263183 MGI
involved in glucose homeostasis IMP
IMP: Inferred from mutant phenotype
23263183 MGI
involved in negative regulation of autophagy IMP
IMP: Inferred from mutant phenotype
23263183 MGI
involved in positive regulation of TOR signaling IMP
IMP: Inferred from mutant phenotype
23263183 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related GTP-binding protein A

  • rag A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12276 RRAGA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21744 Rraga Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28261 Rraga Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rraga NCBI NCBI:10670