Micu2 - mitochondrial calcium uptake 2 Gene

Also Known as Efha1; Smhs2; 1110008L20Rik; 4833427E09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68514

Summary

Enables calcium ion binding activity and protein heterodimerization activity. Involved in mitochondrial calcium ion transmembrane transport and positive regulation of mitochondrial calcium ion concentration. Located in mitochondrion. Part of Calcium Channel complex. Orthologous to human MICU2 (mitochondrial calcium uptake 2). [provided by Alliance of Genome Resources, Apr 2022]

Micu2 Products (1)

mRNA Protein Name
NM_028643.3 NP_082919.1 calcium uptake protein 2, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IMP
IMP: Inferred from mutant phenotype
24560927 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24560927 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
24560927 MGI
Biological Process GO Annotation Evidence References Source
involved in mitochondrial calcium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
23409044 MGI
involved in positive regulation of mitochondrial calcium ion concentration IMP
IMP: Inferred from mutant phenotype
23409044 MGI
Cellular Component GO Annotation Evidence References Source
part of calcium channel complex IDA
IDA: Inferred from direct assay
23409044 MGI
located in mitochondrion IMP
IMP: Inferred from mutant phenotype
23409044 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium uptake protein 2, mitochondrial

  • EF hand domain family A1

  • EF-hand domain-containing family member A1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08432 MICU2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21647 Micu2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28165 Micu2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Micu2 NCBI NCBI:221154