Flnc - filamin C, gamma Gene

Also Known as ABPL; Fln2; ABP-280; 1110055E19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68794

Summary

Predicted to enable ankyrin binding activity and identical protein binding activity. Involved in muscle cell development. Predicted to be located in cytosol; sarcolemma; and sarcoplasm. Is expressed in several structures, including diaphragm; embryo mesenchyme; heart; skeletal musculature; and spinal cord ventricular layer. Used to study myofibrillar myopathy 5. Human ortholog(s) of this gene implicated in distal muscular dystrophy 4; hypertrophic cardiomyopathy 26; and myofibrillar myopathy 5. Orthologous to human FLNC (filamin C). [provided by Alliance of Genome Resources, Apr 2022]

Flnc Products (2)

mRNA Protein Name
NM_001081185.2 NP_001074654.1 filamin-C isoform 1
NM_001311074.2 NP_001298003.1 filamin-C isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in muscle cell development IDA
IDA: Inferred from direct assay
16914736 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

filamin-C

  • ABP-280-like protein

  • actin-binding protein 280

  • actin-binding-like protein

  • filamin-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04981 FLNC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20734 Flnc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27246 Flnc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flnc NCBI NCBI:2318