Vsir - V-set immunoregulatory receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 690899

Summary

Predicted to enable endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Predicted to act upstream of or within several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of T cell cytokine production; and positive regulation of BMP signaling pathway. Predicted to be located in external side of plasma membrane. Orthologous to human VSIR (V-set immunoregulatory receptor). [provided by Alliance of Genome Resources, Apr 2022]

Vsir Products (2)

mRNA Protein Name
NM_001044300.2 NP_001037765.1 V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 1
NM_001399050.1 NP_001385979.1 V-type immunoglobulin domain-containing suppressor of T-cell activation isoform 2
Protein Preferred Names Protein Names

V-type immunoglobulin domain-containing suppressor of T-cell activation

  • platelet receptor Gi24

Recombinant Vsir Proteins

Cat. No. Product Name Accession Purity
HY-P73546 VISTA/B7-H5 Protein, Rat (HEK293, Fc) G3V9P3 (I14-A172) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15711 VSIR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18981 Vsir Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25470 Vsir Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991447 Anti-VSIR/VISTA Antibody (SG7) Inhibitor 98.07% Unkown
HY-P991165 Trovostobart 99.17% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vsir NCBI NCBI:64115