2. Gene
  3. XIAP - X-linked inhibitor of apoptosis Gene

XIAP - X-linked inhibitor of apoptosis Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta

Also known as BIRC4

Gene ID: 698057 | Gene type: protein coding

About XIAP

Primary_assembly X: 120,093,637-120,144,718 forward strand.Mmul_10:CM014356.1

This gene has 4 transcripts (splice variants), 215 orthologues and 8 paralogues.

XIAP Products(4)

mRNA Protein Name
XM_028842530.1 XP_028698363.1 E3 ubiquitin-protein ligase XIAP
XM_015128138.2 XP_014983624.1 E3 ubiquitin-protein ligase XIAP
XM_015128137.2 XP_014983623.1 E3 ubiquitin-protein ligase XIAP
XM_015128136.2 XP_014983622.1 E3 ubiquitin-protein ligase XIAP

XIAP Protein Structure

BIR

BIR: cd00022 (27 - 94)

BIR

BIR: smart00238 (161 - 231)

BIR

BIR: smart00238 (264 - 330)

UBA_BIRC4_8

UBA_BIRC4_8: cd14395 (369 - 418)

RING-HC_BIRC4_8

RING-HC_BIRC4_8: cd16714 (433 - 496)

  • 0
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  • 400
  • 497 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase XIAP

baculoviral IAP repeat-containing 4

baculoviral IAP repeat-containing protein 4

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-15454 Xevinapant Antagonist 99.91% Phase 3
HY-13208 Xevinapant hydrochloride Antagonist 98.11% Phase 3
HY-168739 Topoisomerase I inhibitor 17 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (26)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12600 AZD5582 Antagonist 99.61% Unkown
HY-17473 Embelin Antagonist 99.01% Unkown
HY-N0732 Jolkinolide B Inhibitor 99.65% Unkown
HY-110346 AZD5582 dihydrochloride Antagonist 99.92% Unkown
HY-151966 TD1092 Degrader 99.49% Unkown
HY-178226 PBX-7016 Inhibitor / Unkown
HY-125378 SBP-0636457 Antagonist 98.42% Unkown
HY-175352 Nurr1 agonist 14 Inducer 99.42% Unkown
HY-179633 ZLMT-72 Inhibitor / Unkown
HY-N18315 (2''S)-2'',3''-Dihydrodelicaflavone Modulator / Unkown
HY-111886 KHS108-MV1 Antagonist / Unkown
HY-168893 K882 Inhibitor / Unkown
HY-102051 XIAP/cIAP1 antagonist-1 Inhibitor / Unkown
HY-175348 XB2M54 Antagonist / Unkown
HY-100682 T-3256336 Inhibitor / Unkown
HY-118522 TP-110 Inhibitor / Unkown
HY-175448 GNE-1567 Antagonist / Unkown
HY-175444 XIAP ligand-Linker Conjugate 1 Antagonist / Unkown
HY-181532 IAP ligand 8 Ligand / Unkown
HY-181533 IAP ligand 9 Ligand / Unkown
HY-12440 HM90822 Antagonist / Unkown
HY-123925 CSLP43 Inhibitor / Unkown
HY-179023 CDK9-IN-45 Inhibitor / Unkown
HY-175450 XIAP ligand-Linker Conjugate 2 Antagonist / Unkown
HY-181018 Topo I/DDX5-IN-1 Inhibitor / Unkown
HY-175449 XIAP ligand 5 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens XIAP NCBI NCBI:331