XIAP degrader-1
Based on 1 publication(s) in Google Scholar
XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP).
For research use only. We do not sell to patients.
- Purity: 98.11%
- CAS No.: 2803617-91-4
- Formula: C34H45N5O4
- Molecular Weight:587.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Anti-Cancer Compound Library
HY-L025
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Anti-Prostate Cancer Compound Library
HY-L124
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Anti-Ovarian Cancer Compound Library
HY-L173
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Publications Citing Use of MedChemExpress (MCE) XIAP degrader-1
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Biological Activity
Chemical Information
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CAS No. 2803617-91-4
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Appearance Solid
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Molecular Weight 587.75
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Formula C34H45N5O4
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Color Off-white to light yellow
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SMILES
CN[C@H](C(N[C@@H]1C(N(C2=C(N([C@H]1C)C(CCCCCCCN)=O)C=CC=C2)CC3=C(C=CC=C4)C4=CC=C3OC)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
2024 Jun 26;15(1):5409. PMID: 38926334
Solvent & Solubility
DMSO : 100 mg/mL (170.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7014 mL | 8.5070 mL | 17.0140 mL | 42.5351 mL |
| 5 mM | 0.3403 mL | 1.7014 mL | 3.4028 mL | 8.5070 mL | |
| 10 mM | 0.1701 mL | 0.8507 mL | 1.7014 mL | 4.2535 mL | |
| 15 mM | 0.1134 mL | 0.5671 mL | 1.1343 mL | 2.8357 mL | |
| 20 mM | 0.0851 mL | 0.4254 mL | 0.8507 mL | 2.1268 mL | |
| 25 mM | 0.0681 mL | 0.3403 mL | 0.6806 mL | 1.7014 mL | |
| 30 mM | 0.0567 mL | 0.2836 mL | 0.5671 mL | 1.4178 mL | |
| 40 mM | 0.0425 mL | 0.2127 mL | 0.4254 mL | 1.0634 mL | |
| 50 mM | 0.0340 mL | 0.1701 mL | 0.3403 mL | 0.8507 mL | |
| 60 mM | 0.0284 mL | 0.1418 mL | 0.2836 mL | 0.7089 mL | |
| 80 mM | 0.0213 mL | 0.1063 mL | 0.2127 mL | 0.5317 mL | |
| 100 mM | 0.0170 mL | 0.0851 mL | 0.1701 mL | 0.4254 mL |
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