Mzb1 - marginal zone B and B1 cell-specific protein 1 Gene

Also Known as PACAP; pERp1; 2010001M09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69816

Summary

Involved in several processes, including Integrin activation; positive regulation of immunoglobulin production; and regulation of B cell proliferation. Located in endoplasmic reticulum lumen and extracellular region. Part of endoplasmic reticulum chaperone complex. Is expressed in thymus primordium. Orthologous to human MZB1 (marginal zone B and B1 cell specific protein). [provided by Alliance of Genome Resources, Apr 2022]

Mzb1 Products (1)

mRNA Protein Name
NM_027222.3 NP_081498.2 marginal zone B- and B1-cell-specific protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21093319 MGI
Biological Process GO Annotation Evidence References Source
involved in integrin activation IMP
IMP: Inferred from mutant phenotype
21093319 MGI
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
21688198 MGI
involved in positive regulation of immunoglobulin production IMP
IMP: Inferred from mutant phenotype
19805154 MGI
involved in regulation of B cell proliferation IMP
IMP: Inferred from mutant phenotype
21093319 MGI
involved in regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
21093319 MGI
involved in regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
21688198 MGI
Cellular Component GO Annotation Evidence References Source
part of endoplasmic reticulum chaperone complex IDA
IDA: Inferred from direct assay
19805157 MGI
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
21093319 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
21688198 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

marginal zone B- and B1-cell-specific protein

  • plasma cell-induced ER protein 1

  • plasma cell-induced resident ER protein

  • plasma cell-induced resident endoplasmic reticulum protein

  • proapoptotic caspase adapter protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08976 MZB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19148 Mzb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25639 Mzb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mzb1 NCBI NCBI:51237