Cgn - cingulin Gene

Also Known as 6330408J11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70737

Summary

Enables microtubule binding activity. Acts upstream of or within bicellular tight junction assembly; epithelial cell morphogenesis; and microtubule Cytoskeleton organization. Located in bicellular tight junction and brush border. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; pituitary gland; and respiratory system. Orthologous to human CGN (cingulin). [provided by Alliance of Genome Resources, Apr 2022]

Cgn Products (2)

mRNA Protein Name
NM_001037711.3 NP_001032800.3 cingulin isoform 1
NM_001293727.2 NP_001280656.2 cingulin isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
24385485 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24385485 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within bicellular tight junction assembly IMP
IMP: Inferred from mutant phenotype
24385485 MGI
acts upstream of or within epithelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
24385485 MGI
acts upstream of or within microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
24385485 MGI
Cellular Component GO Annotation Evidence References Source
located in apical junction complex IDA
IDA: Inferred from direct assay
15292197 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
22946046 MGI
located in brush border IDA
IDA: Inferred from direct assay
22114352 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cingulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111793A NUCC-390 dihydrochloride Agonist 98.19% Unkown
HY-111793 NUCC-390 Agonist 98.01% Unkown
HY-P10942A CGN peptide TFA 98.10% Unkown
HY-P10942 CGN peptide / Unkown
HY-RS02585 CGN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18732 Cgn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25219 Cgn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cgn NCBI NCBI:57530