Rptor - regulatory associated protein of MTOR, complex 1 Gene

Also Known as Rap; Raptor; mKIAA1303; 4932417H02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74370

Summary

This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded protein may regulate the assembly, localization, and substrate binding of the mTORC1 complex. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Rptor Products (2)

mRNA Protein Name
NM_001306081.1 NP_001293010.1 regulatory-associated protein of mTOR isoform 2
NM_028898.3 NP_083174.2 regulatory-associated protein of mTOR isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18046414 MGI
Biological Process GO Annotation Evidence References Source
involved in TORC1 signaling IMP
IMP: Inferred from mutant phenotype
27879318 MGI
involved in negative regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
23092880 MGI
involved in positive regulation of odontoblast differentiation IMP
IMP: Inferred from mutant phenotype
30984011 MGI
involved in positive regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
27879318 MGI
involved in regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
23092880 MGI
involved in response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
33495318 MGI
involved in social behavior IMP
IMP: Inferred from mutant phenotype
33495318 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regulatory-associated protein of mTOR

  • p150 target of rapamycin (TOR)-scaffold protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12274 RPTOR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20485 Rptor Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26993 Rptor Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rptor NCBI NCBI:57521