Pomk - protein-O-mannose kinase Gene

Also Known as Sgk196; 4930444A02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74653

Summary

Enables carbohydrate kinase activity. Acts upstream of or within several processes, including learning or memory; nervous system development; and sensory perception of pain. Located in endoplasmic reticulum membrane. Is expressed in cerebral cortex. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A12 and limb-girdle muscular dystrophy. Orthologous to human POMK (protein O-mannose kinase). [provided by Alliance of Genome Resources, Apr 2022]

Pomk Products (1)

mRNA Protein Name
NM_029037.4 NP_083313.1 protein O-mannose kinase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carbohydrate kinase activity IDA
IDA: Inferred from direct assay
23929950 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within neuromuscular process IMP
IMP: Inferred from mutant phenotype
21746835 MGI
involved in protein O-linked glycosylation IDA
IDA: Inferred from direct assay
23929950 MGI
acts upstream of or within sensory perception of pain IMP
IMP: Inferred from mutant phenotype
21746835 MGI
Cellular Component GO Annotation Evidence References Source
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
23929950 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
23929950 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein O-mannose kinase

  • probable inactive protein kinase-like protein SgK196

  • sugen kinase 196

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10868 POMK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17892 Pomk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24361 Pomk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pomk NCBI NCBI:84197