Il34 - interleukin 34 Gene

Also Known as 2010004A03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76527

Summary

Predicted to enable cytokine activity; identical protein binding activity; and macrophage colony-stimulating factor receptor binding activity. Involved in microglial cell proliferation; positive regulation of gene expression; and positive regulation of oligodendrocyte differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and mammary gland. Orthologous to human IL34 (interleukin 34). [provided by Alliance of Genome Resources, Apr 2022]

Il34 Products (2)

mRNA Protein Name
NM_001135100.2 NP_001128572.1 interleukin-34 isoform 1 precursor
NM_029646.3 NP_083922.1 interleukin-34 isoform 2 precursor
Protein Preferred Names Protein Names

interleukin-34

Recombinant Il34 Proteins

Cat. No. Product Name Accession Purity
HY-P73212 IL-34 Protein, Mouse (HEK293, His) Q8R1R4-1 (N21-P235) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700209AF Animal-Free IL-34 Protein, Mouse (His) Q8R1R4-1 (N21-P235) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991048 AMG-820 Inhibitor 98% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06758 IL34 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174606 Human IL34 mRNA / Unkown
HY-RS17538 Il34 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23995 Il34 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992249 Anti-IL-34 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il34 NCBI NCBI:146433