Dtl - denticleless E3 ubiquitin protein ligase Gene
Also Known as Ramp; L2dtl; 2810047L02Rik; 5730564G15Rik
Species: Mus musculus
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including protein ubiquitination; regulation of G2/M transition of mitotic cell cycle; and translesion synthesis. Predicted to act upstream of or within DNA replication and rhythmic process. Predicted to be located in centrosome; cytosol; and nuclear lumen. Predicted to be part of Cul4A-RING E3 ubiquitin Ligase complex and Cul4B-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including brain ventricular layer; genitourinary system; hemolymphoid system gland; lung; and medulla oblongata part of 4th ventricle choroid plexus. Orthologous to human DTL (denticleless E3 ubiquitin protein Ligase homolog). [provided by Alliance of Genome Resources, Apr 2022]
Dtl Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001305233.1 | NP_001292162.1 | denticleless protein homolog isoform 2 |
| NM_029766.3 | NP_084042.1 | denticleless protein homolog isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
denticleless protein homolog |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS19108 | Dtl Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS04034 | DTL Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14824 | TNFSF13B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25598 | Dtl Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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