Sbf1 - SET binding factor 1 Gene

Also Known as Mtmr5; mKIAA3020; 2610510A08Rik; B230113C15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 77980

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within spermatogenesis. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and membrane. Is expressed in craniocervical region bone; nervous system; and neural retina. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B3. Orthologous to human SBF1 (SET binding factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sbf1 Products (2)

mRNA Protein Name
NM_001081030.2 NP_001074499.2 myotubularin-related protein 5 isoform 2
NM_001170561.1 NP_001164032.1 myotubularin-related protein 5 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
11994405 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myotubularin-related protein 5

  • inactive phosphatidylinositol 3-phosphatase 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148391 23-Oxa-OSW-1 Inhibitor / Unkown
HY-RS12464 SBF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19159 Sbf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25648 Sbf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sbf1 NCBI NCBI:6305