Spacdr - sperm acrosome developmental regulator Gene

Also Known as Tilz2; Tsc22d4; Thg-1pit; 0610009M14Rik; 1700023B23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78829

Summary

Acts upstream of or within response to osmotic stress. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and nervous system. Orthologous to several human genes including TSC22D4 (TSC22 domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Spacdr Products (1)

mRNA Protein Name
NM_023910.7 NP_076399.4 TSC22 domain family protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23305244 MGI
Biological Process GO Annotation Evidence References Source
involved in glucose homeostasis IMP
IMP: Inferred from mutant phenotype
27827363 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23307490 MGI
involved in neuron cellular homeostasis IMP
IMP: Inferred from mutant phenotype
20878296 MGI
involved in neuron projection extension IMP
IMP: Inferred from mutant phenotype
20878296 MGI
acts upstream of or within response to osmotic stress IDA
IDA: Inferred from direct assay
17147695 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19084601 MGI
located in dendrite IDA
IDA: Inferred from direct assay
20878296 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19084601 MGI
located in synapse IDA
IDA: Inferred from direct assay
20878296 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TSC22 domain family protein 4

  • TSC22 domain family 4

  • TSC22 domain family, member 4

  • TSC22-related inducible leucine zipper 2

  • TSC22-related-inducible leucine zipper protein 2

Spacdr Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tsc22d4 Q9EQN3 Tsc22d1 Mus musculus P62500
Anti Bait CoIP
23305244
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13619 SPACDR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15136 TSC22D4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spacdr NCBI NCBI:402573