Wsb1 - WD repeat and SOCS box-containing 1 Gene

Also Known as 1110056B13Rik; 2700038M07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78889

Summary

Enables ubiquitin protein Ligase activity. Involved in protein K27-linked ubiquitination. Acts upstream of or within protein aggregate center assembly. Located in cytoplasm. Is expressed in nervous system and neural retina. Orthologous to human WSB1 (WD repeat and SOCS box containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Wsb1 Products (2)

mRNA Protein Name
NM_001042565.3 NP_001036030.1 WD repeat and SOCS box-containing protein 1 isoform 2
NM_019653.3 NP_062627.3 WD repeat and SOCS box-containing protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27273569 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
27273569 MGI
Biological Process GO Annotation Evidence References Source
involved in protein K27-linked ubiquitination IDA
IDA: Inferred from direct assay
27273569 MGI
acts upstream of or within protein aggregate center assembly IDA
IDA: Inferred from direct assay
27273569 MGI
acts upstream of or within protein aggregate center assembly IMP
IMP: Inferred from mutant phenotype
27273569 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
27273569 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat and SOCS box-containing protein 1

  • WD-40-repeat-containing protein with a SOCS box 1

  • WSB-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141482 WSB1 Degrader 1 Inhibitor 99.81% Unkown
HY-RS15849 WSB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20350 Wsb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26859 Wsb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wsb1 NCBI NCBI:26118