2. Gene
  3. GID4 - GID complex subunit 4 homolog Gene

GID4 - GID complex subunit 4 homolog Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as VID2; VID24; C17orf39

Gene ID: 79018 | Gene type: protein coding

About GID4

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:18,039,408-18,068,405 (from NCBI)

This gene has 5 transcripts (splice variants) and 260 orthologues. Broad expression in testis (RPKM 9.8), esophagus (RPKM 5.1) and 25 other tissues.

Summary

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GID4 Products(2)

mRNA Protein Name
NM_001411057.1 NP_001397986.1 glucose-induced degradation protein 4 homolog isoform 2
NM_024052.5 NP_076957.3 glucose-induced degradation protein 4 homolog isoform 1

GID4 Protein Structure

Vac_ImportDeg

Vac_ImportDeg: Vacuolar import and degradation protein (121 - 289)

  • 0
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  • 200
  • 300 a.a.
Protein Preferred Names Protein Names

glucose-induced degradation protein 4 homolog

GID complex subunit 4, VID24 homolog

Related Diseases

Diseases Alias
Smith-Magenis Syndrome

SMS

Chromosome 17p11.2 Deletion Syndrome

17p11.2 Microdeletion Syndrome

17p11.2 Monosomy

Chromosome 17p Deletion Syndrome

Del(17)

P11.2

17p- Syndrome

Deletion 17p Syndrome

Partial Monosomy 17p
Malignant Giant Cell Tumor

Malignant Tumor, Giant Cell Type

Malignant Giant Cell Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-151475 GID4 Ligand 1 / Unkown
HY-151476 GID4 Ligand 2 / Unkown
HY-151479 GID4 Ligand 3 / Unkown
HY-RS05419 GID4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GID4 MGD MGI:1914021
Macaca mulatta GID4 VGNC VGNC:104604
Rattus norvegicus GID4 RGD RGD:1588894
Bos taurus GID4 VGNC VGNC:55833
Canis familiaris GID4 VGNC VGNC:49858
Felis catus GID4 VGNC VGNC:62549