2. Gene
  3. ATAT1 - alpha tubulin acetyltransferase 1 Gene

ATAT1 - alpha tubulin acetyltransferase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TAT; MEC17; C6orf134; Nbla00487; alpha-TAT; alpha-TAT1

Gene ID: 79969 | Gene type: protein coding

About ATAT1

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,626,874-30,646,821 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele and 191 orthologues. Ubiquitous expression in brain (RPKM 7.7), testis (RPKM 3.5) and 23 other tissues.

Summary

This gene encodes a protein that localizes to clathrin-coated pits, where it acetylates alpha tubulin on lysine 40. This process may be important in microtubule growth, for instance during chemotaxis and the formation of cilium. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ATAT1 Products(7)

mRNA Protein Name
NM_001031722.4 NP_001026892.1 alpha-tubulin N-acetyltransferase 1 isoform 1 precursor
NM_001190724.4 NP_001177653.1 alpha-tubulin N-acetyltransferase 1 isoform 3 precursor
NM_001254952.4 NP_001241881.1 alpha-tubulin N-acetyltransferase 1 isoform 4
NM_001318762.3 NP_001305691.1 alpha-tubulin N-acetyltransferase 1 isoform 5
NM_001318763.3 NP_001305692.1 alpha-tubulin N-acetyltransferase 1 isoform 6
NM_001413067.1 NP_001399996.1 alpha-tubulin N-acetyltransferase 1 isoform 7
NM_024909.5 NP_079185.2 alpha-tubulin N-acetyltransferase 1 isoform 2

ATAT1 Protein Structure

Acetyltransf_16

Acetyltransf_16: GNAT acetyltransferase, Mec-17 (72 - 192)

  • 0
  • 100
  • 200
  • 300
  • 421 a.a.
Protein Preferred Names Protein Names

alpha-tubulin N-acetyltransferase 1

acetyltransferase mec-17 homolog

Related Diseases

Diseases Alias
Spherocytosis, Type 1

Hereditary Spherocytosis Type 1

SPH1

Hs1

Spherocytosis, Hereditary, 1

Sph

Hs

Hereditary Spherocytosis 1

Spherocytosis 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01124 ATAT1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ATAT1 MGD MGI:1913869
Felis catus ATAT1 VGNC VGNC:59992
Canis familiaris ATAT1 VGNC VGNC:38204
Rattus norvegicus ATAT1 RGD RGD:1303066
Bos taurus ATAT1 VGNC VGNC:26236
Macaca mulatta ATAT1 VGNC VGNC:70106