Mlh1 - mutL homolog 1 Gene
Species: Rattus norvegicus
Summary
Predicted to enable several functions, including ATP hydrolysis activity; chromatin binding activity; and guanine/thymine mispair binding activity. Predicted to contribute to MutSalpha complex binding activity and single-stranded DNA binding activity. Involved in several processes, including response to hypoxia; response to toxic substance; and spermatogenesis. Located in synaptonemal complex. Used to study lung carcinoma. Human ortholog(s) of this gene implicated in Lynch syndrome (multiple); gastrointestinal system Cancer (multiple); lung cancer; mismatch repair Cancer syndrome; and sporadic breast Cancer. Orthologous to human MLH1 (mutL homolog 1). [provided by Alliance of Genome Resources, Apr 2022]
Mlh1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_031053.2 | NP_112315.2 | DNA mismatch repair protein Mlh1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
DNA mismatch repair protein Mlh1 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-147149 | BPN-15477 | Modulator | 99.92% | Unkown |
| HY-RS08489 | MLH1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19146 | Mlh1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25637 | Mlh1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service